A Stability-Indicating High Performance Liquid Chromatographic Method For the Determination of Nelarabine
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چکیده
منابع مشابه
A Stability-Indicating High Performance Liquid Chromatographic Method For the Determination of Nelarabine
The present study describes the development and validation of stability indicating RP HPLC method for the estimation of nelarabine, a chemotherapy drug. Nelarabine was subjected to stress studies under different conditions as per ICH guidelines. The separations were carried out using C18 Reverse Phase Column (Cosmicsil Adge 150 x 4.6 mm, 5μm) employing 0.01 % trifluoroacetic acid and acetonitri...
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A stability-indicating HPLC method was developed and validated for the quantitative determination of diacerein in capsule dosage forms. An isocratic separation was achieved using a perfectsil target ODS-3, 250x4.6 mm i.d., 5 microm particle size columns with a flow rate of 1 ml/min and using a UV detector to monitor the eluate at 254 nm. The mobile phase consisted of phosphate buffer:acetonitri...
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Dabigatran Etexilate Mesylate was subjected to different ICH recommended stress conditions. Degradation of drug occurs almost in all conditions (hydrolytic, oxidative and photolytic) while mild degradation was seen with thermal stress. A validated stability-indicating HPLC method was developed for the analysis of drug in presence of its degradation products. The stressed samples of drug were an...
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A novel stability-indicating high-performance liquid chromatographic assay method was developed and validated for valacyclovir in the presence of degradation products generated from forced decomposition studies. A Hypersil ODS C-18 (250 x 4.6 mm, packed with 5 micron) column in an isocratic mode with the mobile phase acetonitrile: phosphate buffer (pH3.6) (50:50%v/v) was used. The flow rate was...
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ژورنال
عنوان ژورنال: Oriental Journal of Chemistry
سال: 2016
ISSN: 0970-020X,2231-5039
DOI: 10.13005/ojc/320168